The Zyxin antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to ZYX, and Zyxin. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Zyxin antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin(ZYX) is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles